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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRSK1
All Species:
13.03
Human Site:
S415
Identified Species:
28.67
UniProt:
Q8TDC3
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDC3
NP_115806.1
794
86753
S415
K
R
R
P
E
R
K
S
M
E
V
L
S
I
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541413
801
87720
S422
K
R
R
P
E
R
K
S
M
E
V
L
S
I
T
Cat
Felis silvestris
Mouse
Mus musculus
Q5RJI5
778
85136
S399
K
R
R
P
E
R
K
S
M
E
V
L
S
I
T
Rat
Rattus norvegicus
O08679
722
80853
S345
T
R
E
E
I
Q
D
S
L
V
G
Q
R
Y
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514667
306
34673
Chicken
Gallus gallus
Q9IA88
798
88848
I397
Y
Q
Q
P
Q
S
L
I
Q
P
S
L
Q
A
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
S513
Q
L
E
Y
K
E
Q
S
L
L
Q
P
P
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648814
861
95238
S388
A
P
S
Y
G
Q
I
S
E
G
S
P
L
T
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
R541
A
S
P
S
R
Y
S
R
S
S
A
T
A
T
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
M160
V
E
Y
C
H
R
N
M
V
V
H
R
D
L
K
Baker's Yeast
Sacchar. cerevisiae
P34244
1518
169574
T519
L
E
I
H
S
E
D
T
S
T
V
N
Q
N
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
98.1
N.A.
94.8
29.2
N.A.
32.1
28.3
N.A.
25.1
N.A.
48.5
N.A.
25.7
N.A.
Protein Similarity:
100
N.A.
N.A.
98.2
N.A.
95.4
44.5
N.A.
33.3
43.9
N.A.
38.5
N.A.
62.5
N.A.
37.9
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
13.3
N.A.
0
13.3
N.A.
6.6
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
26.6
N.A.
0
33.3
N.A.
33.3
N.A.
13.3
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27
22.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.9
34.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
0
0
0
0
0
0
0
10
0
10
10
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
19
0
0
0
0
0
10
0
0
% D
% Glu:
0
19
19
10
28
19
0
0
10
28
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
10
10
0
0
0
10
% G
% His:
0
0
0
10
10
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
10
0
10
0
10
10
0
0
0
0
0
28
0
% I
% Lys:
28
0
0
0
10
0
28
0
0
0
0
0
0
0
10
% K
% Leu:
10
10
0
0
0
0
10
0
19
10
0
37
10
10
10
% L
% Met:
0
0
0
0
0
0
0
10
28
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
10
0
10
19
% N
% Pro:
0
10
10
37
0
0
0
0
0
10
0
19
10
0
10
% P
% Gln:
10
10
10
0
10
19
10
0
10
0
10
10
19
0
0
% Q
% Arg:
0
37
28
0
10
37
0
10
0
0
0
10
10
0
0
% R
% Ser:
0
10
10
10
10
10
10
55
19
10
19
0
28
0
0
% S
% Thr:
10
0
0
0
0
0
0
10
0
10
0
10
0
28
28
% T
% Val:
10
0
0
0
0
0
0
0
10
19
37
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
10
19
0
10
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _